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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.
Antibodies conjugated with drugs at the FC region are designed to attach a drug to the FC region of the antibody. This technology leverages the specificity of antibodies to deliver the drug directly to target cells. As a result, it can enhance the drug's effectiveness and reduce side effects. This approach is particularly promising in cancer treatment and therapies for autoimmune diseases.
3D cartoon and Gaussian surface models, PDB 6vg8, white background
A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin.  Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease.  Isolated on white.
Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.
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Cytochrome P450 molecule. CYP 3A4 is the most promiscuous of the human CYP enzymes. Molecular model. 3D rendering. Illustration
Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus
Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria.  Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.
Colorful Molecules Background
3D cartoon and Gaussian surface models. PDB 2aai, white background.
A model of a molecule of arginine, an amino acid. Amino acids are the building blocks of proteins and have many functions in metabolism. In particular, Arginine has an important function in the immune system, wound healing and cell division.
Botulinum toxin neurotoxic protein, 3D rendering. Produced by Clostridium botulinum. Cosmetically used to treat wrinkles.
Amino Acid Lysine
Beta-alanine or β-Alanine molecule. It is naturally occurring beta amino acid. Molecular model. 3D rendering. Illustration
Multi-colored connected spheres building a molecular structure.
PETase (left) degrades  polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.
Scientific background. 3D render.
3D cartoon and Gaussian surface models, PDB 3hg3, white background
A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.
Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.
DNA A-T Pair
Cholera toxin, molecular model. Cholera toxin (choleragen) is a protein complex secreted by the bacterium Vibrio cholerae, that causes the disease cholera. It is made up of a wedge-shaped A subunit (right part of illustration) and five B subunits (left part of illustration) that form a ring which binds to the intestinal lining. In its most severe forms, cholera is one of the most rapidly fatal illnesses known.
Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, based on the chemical structure available in public space from U.S. National Library of Medicine, which was professionally checked. Color symbols - green=carbon, red=oxygen, blue=nitrogen, white=hydrogen, purple=phosphorus
Abstract Pink And Green Knot
3D molecule model isolated on black. Clipping path included.Similar images:
3D cartoon and Gaussian surface models, chain id color scheme, PDB 5y0m, white background
A ball and stick model of a molecule of Human Glucagon, a hormone produced in the pancreas and used by the body to raise levels of glucose in the blood. Glucagon worksin the opposite manner to Insulin, which lowers levels of glucose in the blood - together they work to keep glucose levels stable.
D-aspartic acid (D-aspartate) amino acid molecule. 3D rendering. Atoms are represented as spheres with conventional color coding.
Free Images: "bestof:PDB 1gk0 EBI.jpg Alpha and beta proteins a+b Ntn hydrolase-like N-terminal nucleophile aminohydrolases Ntn hydrolases Penicillin acylase catalytic domain"
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