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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.
A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin. Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease. Isolated on white.
c-Myc and Max transcription factors bound to DNA. 3D illustration. Atoms shown as spheres with conventional color coding.
Abstract geometric shape
3D cartoon and Gaussian surface models. PDB 2aai, white background.
DNA A-T Pair
Cytochrome P450 molecule. CYP 3A4 is the most promiscuous of the human CYP enzymes. Molecular model. 3D rendering. Illustration
Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus
Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria. Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.
A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.
Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.
3d Rendering Abstract Molecule Background
3D cartoon and Gaussian surface models, chain id color scheme, PDB 5y0m, white background
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Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration
Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, based on the chemical structure available in public space from U.S. National Library of Medicine, which was professionally checked. Color symbols - green=carbon, red=oxygen, blue=nitrogen, white=hydrogen, purple=phosphorus
PETase (left) degrades polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.
A ball and stick model of a molecule of gamma-Cyclodextrin. Composed of eight glucose sugar molecules bound into a ring structure, cyclodextrins are easily made from simple starch. The large ring can bind smaller molecules within it, making Cylodextrins useful in drug-delivery applications and also to clean up toxins (such as heavy metals) in the environment. Currently, gamma-Cyclodextrin is being considered as a structure which can bind to and hold carbon dioxide gas for carbon capture and storage as a way to manage the effect of excess carbon dioxide on the climate.
Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.
Human had writing word endorphins and chemical formula. Endorphins are among the brain chemicals known as neurotransmitters, which function to transmit electrical signals within the nervous system
3D cartoon and Gaussian surface models, PDB 4cmh, white background
Model of human Insulin, a hormone to regulate carbohydrate and fat metabolism
Abstract Pink And Green Knot
Spherical molecule render. The model is isolated on white and could be easily extracted as well as used with the background.
Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration
A ball and stick model of a molecule of Human Glucagon, a hormone produced in the pancreas and used by the body to raise levels of glucose in the blood. Glucagon worksin the opposite manner to Insulin, which lowers levels of glucose in the blood - together they work to keep glucose levels stable.
Botulinum toxin neurotoxic protein, 3D rendering. Produced by Clostridium botulinum. Cosmetically used to treat wrinkles.
Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, which was professionally checked. Color symbols - light blue=carbon, red=oxygen, blue=nitrogen, white=hydrogen, green=phosphorus
3D cartoon and Gaussian surface models, PDB 3hg3, white background
Molecular model of Adenosine triphosphate, or Adenosine-5'-triphosphate (ATP)
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